Effects of Fenofibrate on myocardial remodeling in spontaneous hypertensive rats evaluated by Echoca

    Objective: To assess the effects of Fenofibrate on myocardial remo-deling in SHR by Echocardiography.      

    Methods: SHR were randomly divided into two groups: Fenofibrate group, SHR-controlled group.The same week-old Wistar-kyoto(WKY) rats group was also randomly selected. The Fenofibrate group weregiven drugs（Fenofibrate 60mg/kg.d^-1）for 8 weeks.Echocardiographic scan was performed in each group before and after the experiment.Results: At the ending of the experiment, compared with the WKYgroup , the ventricular thickness and left ventricular relative mass inSHR-controlled group were significantly increased (2.60±0.34 vs 1.82±0.10, 2.49±0.24 vs 1.84±0.

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