Therapeutic monitoring of cyclosporine C0C2 concentration after heart transplantation
作者:张海波 出处:北京安贞医院心外科
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PURPUSE To explore the clinical effect of cyclosporine C2 concentration (2 hr post-dose level) monitoring in the management of heart transplantation recipients. METHODS We performed 31 cases heart transplant between 1992 to 2006. 20 Cases received cyclosporine trough level monitoring and 11 cases received C0C2 monitoring. The donor and recipient weight mismatch is less than 20% and PRA less than 10%. The cold modified St. Thomas solution was use for the donor myocardial protection. All the patients received cyclosporine, mycophenolate mofetil and prednisone for the immune inhibition. Cyclosporine (Neoral) was used orally with 2mg/kg/day 2 times a day as the onset dose. Our aimed C0 concentration r
发布人:onetwofree 发布时间:2006年8月17日
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