Efficacy of Radiofrequency Catheter Ablation on Non-Pulmonary Vein Originated Atrial Fibrillation

    Background: Pulmonary vein (PV) has been demonstrated to be important for initiation of Paroxysmal Atrial fibrillation (PAF), and PV isolation has become a major strategy for treatment of PAF. Non-PV foci also play essential roles in some PAF patients. However, only limited data could be found for evaluation of non-PV foci ablation.

    Methods and results: Two hundred and fifty six patients (62 female, mean age 53±12 ys.) with PAF were included. During the electrophysiologic study, twenty-seven patients (10.5%) were found with ectopic foci in non-PV areas (Group NPV), including the superior vena cava (16, 59.3%), left atrial posterial wall (4, 14.8%), crista terminalis (2, 7.4%), coronary sinus (

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