AbstractCardiac resynchronization therapy with biventricular pacing improves quality of life and survival in individuals with systolic heart failure. A significant issue with cardiac resynchronization therapy at the present time is the clear identification of responders versus non-responders. Various clinical, electrocardiographic and echocardiographic predictors of response have been described. Most clinical trials have utilized QRS widening as marker of ventricular dyssynchrony. However, 20 – 30% of patients satisfying these criteria do not respond well to resynchronization. Newer criteria for detection of ventricular dyssynchrony are emerging. Echocardiographic evidence of ventricular dyssynchrony has been found in t
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